SC-31155 |
Part Number | SC-31155 |
Manufacturer | Santa Cruz Biotechnology |
Description | SANTA CRUZ BIOTECHNOLOGY, INC. www.DataSheet4U.com EGFR (N-20): sc-31155 The Power to Question BACKGROUND The EGF receptor family comprises several related receptor tyrosine kinases that are frequen... |
Features |
of tissues, but upregulation of EGFR is associated with tumor progression. The oncogenic effects of EGFR include initiation of DNA synthesis, enhanced cell growth, invasion and metastasis. Abrogation of EGFR results in cell cycle arrest, apoptosis or dedifferentiation of cancer cells, suggesting that EGFR may be an effective therapeutic target.
APPLICATIONS
EGFR (N-20) is recommended for detection of EGF receptor of mouse, rat and human origin by Western Blotting (starting dilution 1:200, dilution range 1:100-1:1000), immunoprecipitation [1 –2 µg per 100 –500 µg of total protein (1 ml of cell l... |
Document |
SC-31155 Data Sheet
PDF 93.92KB |
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